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Elaine M Hurt Selected Research

MEDI0641

5/20175T4-Targeted Therapy Ablates Cancer Stem Cells and Prevents Recurrence of Head and Neck Squamous Cell Carcinoma.
1/2017Preclinical Evaluation of MEDI0641, a Pyrrolobenzodiazepine-Conjugated Antibody-Drug Conjugate Targeting 5T4.

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Elaine M Hurt Research Topics

Disease

28Neoplasms (Cancer)
11/2023 - 06/2002
11Prostatic Neoplasms (Prostate Cancer)
11/2023 - 08/2006
6Multiple Myeloma
01/2020 - 06/2005
4Tics (Tic)
02/2012 - 06/2009
2Head and Neck Neoplasms (Head and Neck Cancer)
01/2020 - 01/2016
2Neoplasm Metastasis (Metastasis)
01/2020 - 11/2008
2Squamous Cell Carcinoma of Head and Neck
05/2017 - 01/2016
2Carcinoma (Carcinomatosis)
01/2017 - 11/2008
2Carcinogenesis
10/2008 - 02/2007
2Inflammation (Inflammations)
11/2005 - 06/2005
1Squamous Cell Carcinoma (Epidermoid Carcinoma)
01/2020
1Pancreatic Neoplasms (Pancreatic Cancer)
07/2011
1Brain Neoplasms (Brain Tumor)
09/2010
1Endometrial Neoplasms (Endometrial Cancer)
11/2008
1Infections
11/2005
1X-Linked Combined Immunodeficiency Diseases (X Linked Severe Combined Immunodeficiency)
02/2003
1Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse)
06/2002

Drug/Important Bio-Agent (IBA)

4Immunoconjugates (Immunoconjugate)IBA
11/2023 - 01/2017
4Androgen Receptors (Androgen Receptor)IBA
11/2023 - 08/2006
4Proteins (Proteins, Gene)FDA Link
01/2020 - 05/2010
3pyrrolo(2,1-c)(1,4)benzodiazepineIBA
11/2023 - 05/2017
3Interleukin-6 (Interleukin 6)IBA
01/2016 - 06/2005
3Messenger RNA (mRNA)IBA
02/2012 - 02/2003
3DNA (Deoxyribonucleic Acid)IBA
07/2011 - 06/2002
3AndrogensIBA
10/2008 - 08/2006
3CytokinesIBA
11/2005 - 02/2003
2AntigensIBA
11/2023 - 01/2017
2A-Form DNA (A-DNA)IBA
11/2023 - 05/2017
2MEDI0641IBA
05/2017 - 01/2017
2PhytochemicalsIBA
02/2010 - 08/2008
2Transcription Factors (Transcription Factor)IBA
06/2009 - 10/2008
2STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA
10/2008 - 11/2005
2EnzymesIBA
05/2007 - 07/2006
1Biomarkers (Surrogate Marker)IBA
11/2023
1Membrane Proteins (Integral Membrane Proteins)IBA
11/2023
1IntegrinsIBA
01/2020
1RimantadineFDA LinkGeneric
01/2020
1bis(3- bis(4- chlorophenyl)methyl- 4- dimethylaminophenyl)amineIBA
01/2019
1Programmed Cell Death 1 ReceptorIBA
01/2018
1Cytotoxins (Cytolysins)IBA
01/2017
1Immunoglobulin G (IgG)IBA
01/2016
1Histones (Histone)IBA
01/2013
1MicroRNAs (MicroRNA)IBA
02/2012
1GemcitabineFDA Link
07/2011
13-deazaneplanocinIBA
04/2011
1Polycomb Repressive Complex 2IBA
04/2011
1AntioxidantsIBA
04/2011
1Docetaxel (Taxotere)FDA Link
04/2011
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
05/2010
1Integrin alphaVbeta3IBA
03/2010
1VitronectinIBA
03/2010
1GossypolIBA
02/2010
1parthenolideIBA
06/2009
1Serum Response FactorIBA
06/2009
1LactonesIBA
06/2009
1SesquiterpenesIBA
06/2009
1CCAAT-Enhancer-Binding Protein-alphaIBA
06/2009
1Zinc Finger E-box-Binding Homeobox 1IBA
11/2008
1Estrogens (Estrogen)FDA Link
11/2008
1Testosterone (Sustanon)FDA Link
10/2008
1Superoxide DismutaseIBA
10/2008
1Tyrosine (L-Tyrosine)FDA Link
10/2008
1Serine (L-Serine)FDA Link
10/2008
1Hormones (Hormone)IBA
10/2008
1NF-kappa B (NF-kB)IBA
08/2007
1Reactive Oxygen Species (Oxygen Radicals)IBA
05/2007
1betaglycan (TGFBR3)IBA
02/2007
1Transforming Growth Factor beta (TGF-beta)IBA
02/2007
1Peptides (Polypeptides)IBA
09/2006
1Thymine DNA GlycosylaseIBA
07/2006
1LigandsIBA
11/2005
1Inflammation MediatorsIBA
06/2005
1MethyltransferasesIBA
06/2005
1Cyclin D2IBA
02/2004
1Interleukin-4 (Interleukin 4)IBA
02/2003
1Interleukin-9 (Interleukin 9)IBA
02/2003
1Interleukin-15 (Interleukin 15)IBA
02/2003
1InterleukinsIBA
02/2003
1Cytokine Receptors (Cytokine Receptor)IBA
02/2003
1Interleukin-7 (Interleukin 7)IBA
02/2003
1interleukin-21 (interleukin 21)IBA
02/2003
1Cyclin D1IBA
02/2003

Therapy/Procedure

14Therapeutics
11/2023 - 02/2003
2Drug Therapy (Chemotherapy)
05/2017 - 06/2002
2Radiotherapy
01/2015 - 12/2012
2Castration
10/2008 - 08/2006
1Immunotherapy
01/2020